"Caspase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its caspase recruitment domain with CARD SIGNALING ADAPTOR PROTEINS. Caspase 2 plays a role in APOPTOSIS by cleaving and activating effector pro-caspases. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053143
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.550.200 D08.811.277.656.300.200.126.550.200 D12.644.360.075.405.550.200 D12.776.476.075.405.550.200
|
| Concept/Terms |
Caspase 2- Caspase 2
- ICH-1 Protease
- ICH 1 Protease
- Caspase-2
Procaspase-2- Procaspase-2
- Procaspase 2
- Pro-Caspase-2
- Pro Caspase 2
|
Below are MeSH descriptors whose meaning is more general than "Caspase 2".
Below are MeSH descriptors whose meaning is more specific than "Caspase 2".
This graph shows the total number of publications written about "Caspase 2" by people in this website by year, and whether "Caspase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caspase 2" by people in Profiles.
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BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer. Cancer Cell. 2017 01 09; 31(1):79-93.