"Basigin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
| Descriptor ID |
D051926
|
| MeSH Number(s) |
D12.776.395.550.045 D12.776.543.550.187 D23.050.285.040
|
| Concept/Terms |
Basigin- Basigin
- Emmprin
- CD147 Antigens
- Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
- Emmprin Protein
- Basigin Protein
- CD147 Antigen
- Antigen, CD147
- Antigens, CD147
|
Below are MeSH descriptors whose meaning is more general than "Basigin".
Below are MeSH descriptors whose meaning is more specific than "Basigin".
This graph shows the total number of publications written about "Basigin" by people in this website by year, and whether "Basigin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 2 | 0 | 2 |
| 2020 | 5 | 2 | 7 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "Basigin" by people in Profiles.
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Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein. mSphere. 2021 08 25; 6(4):e0064721.
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Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns. Placenta. 2021 08; 111:91-96.
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SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2. Cells. 2021 06 08; 10(6).
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Dysregulation of COVID-19 related gene expression in the COPD lung. Respir Res. 2021 May 29; 22(1):164.
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Role of host factors in SARS-CoV-2 entry. J Biol Chem. 2021 07; 297(1):100847.
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Dysbalance of ACE2 levels - a possible cause for severe COVID-19 outcome in COPD. J Pathol Clin Res. 2021 09; 7(5):446-458.
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Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection. Arch Virol. 2021 Aug; 166(8):2089-2108.
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Less Severe Cases of COVID-19 in Sub-Saharan Africa: Could Co-infection or a Recent History of Plasmodium falciparum Infection Be Protective? Front Immunol. 2021; 12:565625.
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Eyes on coronavirus. Stem Cell Res. 2021 03; 51:102200.
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No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor. Sci Rep. 2021 01 11; 11(1):413.