"Fas Ligand Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
| Descriptor ID |
D053222
|
| MeSH Number(s) |
D12.644.276.374.750.249 D12.776.395.550.312 D12.776.467.374.750.249 D12.776.543.550.312 D23.529.374.750.249
|
| Concept/Terms |
Fas Ligand Protein- Fas Ligand Protein
- CD95L
- Fas Ligand (FasL)
- FasL Protein
- TNF Superfamily, Member 6
- CD178 Antigen
- Antigen, CD178
- Antigens, CD178
- Fas Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 6
- CD178 Antigens
- CD95 Antigen Ligand
- CD95 Ligand
|
Below are MeSH descriptors whose meaning is more general than "Fas Ligand Protein".
Below are MeSH descriptors whose meaning is more specific than "Fas Ligand Protein".
This graph shows the total number of publications written about "Fas Ligand Protein" by people in this website by year, and whether "Fas Ligand Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 4 | 1 | 5 |
| 2018 | 3 | 2 | 5 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Fas Ligand Protein" by people in Profiles.
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Immune response to intravenous immunoglobulin in patients with Kawasaki disease and MIS-C. J Clin Invest. 2021 10 15; 131(20).
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Triangle of cytokine storm, central nervous system involvement, and viral infection in COVID-19: the role of sFasL and neuropilin-1. Rev Neurosci. 2022 02 23; 33(2):147-160.
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sFasL-The Key to a Riddle: Immune Responses in Aging Lung and Disease. Int J Mol Sci. 2021 Feb 22; 22(4).
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Identification of a miR-146b-Fas ligand axis in the development of neutropenia in T large granular lymphocyte leukemia. Haematologica. 2020 05; 105(5):1351-1360.
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Interleukin-5 induces apoptotic defects in CD4+ T cells of patients with allergic rhinitis. J Leukoc Biol. 2019 04; 105(4):719-727.
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Platelet-RBC interaction mediated by FasL/FasR induces procoagulant activity important for thrombosis. J Clin Invest. 2018 08 31; 128(9):3906-3925.
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The red blood cell death receptor and thrombosis. J Clin Invest. 2018 08 31; 128(9):3747-3749.
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Matrix metalloproteinase 7, soluble Fas and Fas ligand serum levels for predicting docetaxel resistance and survival in castration-resistant prostate cancer. BJU Int. 2018 10; 122(4):695-704.
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Determinants of Monocyte Apoptosis in Cardiorenal Syndrome Type 1. Cardiorenal Med. 2018; 8(3):208-216.
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Fas/FasL interaction mediates imbalanced cytokine/cytotoxicity responses of iNKT cells against Jurkat cells. Mol Immunol. 2018 07; 99:145-153.