Volker Thiel

InstitutionUniversity of Bern
AddressBern
Switzerland
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 24 Covid-19 publications, with a maximum of 4 publications in April 2021
    All Publications
    Bar chart showing 152 publications over 26 distinct years, with a maximum of 13 publications in 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Trimpert J, Dietert K, Firsching TC, Ebert N, Thi Nhu Thao T, Vladimirova D, Kaufer S, Labroussaa F, Abdelgawad A, Conradie A, Höfler T, Adler JM, Bertzbach LD, Jores J, Gruber AD, Thiel V, Osterrieder N, Kunec D. Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding. Cell Rep. 2021 08 03; 36(5):109493. PMID: 34320400.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    2. Citations: 24     Fields:    Translation:Humans
    3. Gultom M, Licheri M, Laloli L, Wider M, Strässle M, V'kovski P, Steiner S, Kratzel A, Thao TTN, Probst L, Stalder H, Portmann J, Holwerda M, Ebert N, Stokar-Regenscheit N, Gurtner C, Zanolari P, Posthaus H, Schuller S, Vicente-Santos A, Moreira-Soto A, Corrales-Aguilar E, Ruggli N, Tekes G, von Messling V, Sawatsky B, Thiel V, Dijkman R. Susceptibility of Well-Differentiated Airway Epithelial Cell Cultures from Domestic and Wild Animals to Severe Acute Respiratory Syndrome Coronavirus 2. Emerg Infect Dis. 2021 07; 27(7):1811-1820. PMID: 34152956.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    4. Bhatt PR, Scaiola A, Loughran G, Leibundgut M, Kratzel A, Meurs R, Dreos R, O'Connor KM, McMillan A, Bode JW, Thiel V, Gatfield D, Atkins JF, Ban N. Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science. 2021 06 18; 372(6548):1306-1313. PMID: 34029205.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    5. Lei J, Ma-Lauer Y, Han Y, Thoms M, Buschauer R, Jores J, Thiel V, Beckmann R, Deng W, Leonhardt H, Hilgenfeld R, von Brunn A. The SARS-unique domain (SUD) of SARS-CoV and SARS-CoV-2 interacts with human Paip1 to enhance viral RNA translation. EMBO J. 2021 06 01; 40(11):e102277. PMID: 33876849.
      Citations: 5     Fields:    Translation:HumansCells
    6. Stevaert A, Krasniqi B, Van Loy B, Nguyen T, Thomas J, Vandeput J, Jochmans D, Thiel V, Dijkman R, Dehaen W, Voet A, Naesens L. Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15 Endoribonuclease. J Med Chem. 2021 05 13; 64(9):5632-5644. PMID: 33877845.
      Citations: 1     Fields:    Translation:HumansCells
    7. García-Nicolás O, V'kovski P, Zettl F, Zimmer G, Thiel V, Summerfield A. No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection. Front Cell Infect Microbiol. 2021; 11:644574. PMID: 33912475.
      Citations: 9     Fields:    Translation:HumansCells
    8. Stukalov A, Girault V, Grass V, Karayel O, Bergant V, Urban C, Haas DA, Huang Y, Oubraham L, Wang A, Hamad MS, Piras A, Hansen FM, Tanzer MC, Paron I, Zinzula L, Engleitner T, Reinecke M, Lavacca TM, Ehmann R, Wölfel R, Jores J, Kuster B, Protzer U, Rad R, Ziebuhr J, Thiel V, Scaturro P, Mann M, Pichlmair A. Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV. Nature. 2021 06; 594(7862):246-252. PMID: 33845483.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    9. V'kovski P, Gultom M, Kelly JN, Steiner S, Russeil J, Mangeat B, Cora E, Pezoldt J, Holwerda M, Kratzel A, Laloli L, Wider M, Portmann J, Tran T, Ebert N, Stalder H, Hartmann R, Gardeux V, Alpern D, Deplancke B, Thiel V, Dijkman R. Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium. PLoS Biol. 2021 03; 19(3):e3001158. PMID: 33780434.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    10. Citations: 17     Fields:    Translation:HumansCells
    11. Citations: 87     Fields:    Translation:HumansAnimalsCells
    12. Hufsky F, Beerenwinkel N, Meyer IM, Roux S, Cook GM, Kinsella CM, Lamkiewicz K, Marquet M, Nieuwenhuijse DF, Olendraite I, Paraskevopoulou S, Young F, Dijkman R, Ibrahim B, Kelly J, Le Mercier P, Marz M, Ramette A, Thiel V. The International Virus Bioinformatics Meeting 2020. Viruses. 2020 12 06; 12(12). PMID: 33291220.
      Citations:    Fields:    Translation:HumansCells
    13. Gasbarri M, V'kovski P, Torriani G, Thiel V, Stellacci F, Tapparel C, Cagno V. SARS-CoV-2 Inhibition by Sulfonated Compounds. Microorganisms. 2020 Nov 30; 8(12). PMID: 33265927.
      Citations: 4     
    14. Holwerda M, V'kovski P, Wider M, Thiel V, Dijkman R. Identification of an Antiviral Compound from the Pandemic Response Box that Efficiently Inhibits SARS-CoV-2 Infection In Vitro. Microorganisms. 2020 Nov 26; 8(12). PMID: 33256227.
      Citations: 5     
    15. Schubert K, Karousis ED, Jomaa A, Scaiola A, Echeverria B, Gurzeler LA, Leibundgut M, Thiel V, Mühlemann O, Ban N. Author Correction: SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat Struct Mol Biol. 2020 Nov; 27(11):1094. PMID: 33082564.
      Citations: 5     Fields:    
    16. V'kovski P, Kratzel A, Steiner S, Stalder H, Thiel V. Coronavirus biology and replication: implications for SARS-CoV-2. Nat Rev Microbiol. 2021 03; 19(3):155-170. PMID: 33116300.
      Citations: 324     Fields:    Translation:HumansAnimals
    17. Ancar R, Li Y, Kindler E, Cooper DA, Ransom M, Thiel V, Weiss SR, Hesselberth JR, Barton DJ. Physiologic RNA targets and refined sequence specificity of coronavirus EndoU. RNA. 2020 12; 26(12):1976-1999. PMID: 32989044.
      Citations: 4     Fields:    Translation:AnimalsCells
    18. Schubert K, Karousis ED, Jomaa A, Scaiola A, Echeverria B, Gurzeler LA, Leibundgut M, Thiel V, Mühlemann O, Ban N. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation. Nat Struct Mol Biol. 2020 10; 27(10):959-966. PMID: 32908316.
      Citations: 111     Fields:    Translation:HumansCells
    19. Pfaender S, Mar KB, Michailidis E, Kratzel A, Boys IN, V'kovski P, Fan W, Kelly JN, Hirt D, Ebert N, Stalder H, Kleine-Weber H, Hoffmann M, Hoffmann HH, Saeed M, Dijkman R, Steinmann E, Wight-Carter M, McDougal MB, Hanners NW, Pöhlmann S, Gallagher T, Todt D, Zimmer G, Rice CM, Schoggins JW, Thiel V. LY6E impairs coronavirus fusion and confers immune control of viral disease. Nat Microbiol. 2020 11; 5(11):1330-1339. PMID: 32704094.
      Citations: 55     Fields:    Translation:AnimalsCellsPHPublic Health
    20. Kratzel A, Todt D, V'kovski P, Steiner S, Gultom M, Thao TTN, Ebert N, Holwerda M, Steinmann J, Niemeyer D, Dijkman R, Kampf G, Drosten C, Steinmann E, Thiel V, Pfaender S. Inactivation of Severe Acute Respiratory Syndrome Coronavirus 2 by WHO-Recommended Hand Rub Formulations and Alcohols. Emerg Infect Dis. 2020 07; 26(7):1592-1595. PMID: 32284092.
      Citations: 102     Fields:    Translation:HumansCellsPHPublic Health
    21. Kratzel A, Steiner S, Todt D, V'kovski P, Brueggemann Y, Steinmann J, Steinmann E, Thiel V, Pfaender S. Temperature-dependent surface stability of SARS-CoV-2. J Infect. 2020 09; 81(3):452-482. PMID: 32504748.
      Citations: 31     Fields:    Translation:HumansCellsPHPublic Health
    22. Thi Nhu Thao T, Labroussaa F, Ebert N, V'kovski P, Stalder H, Portmann J, Kelly J, Steiner S, Holwerda M, Kratzel A, Gultom M, Schmied K, Laloli L, Hüsser L, Wider M, Pfaender S, Hirt D, Cippà V, Crespo-Pomar S, Schröder S, Muth D, Niemeyer D, Corman VM, Müller MA, Drosten C, Dijkman R, Jores J, Thiel V. Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform. Nature. 2020 06; 582(7813):561-565. PMID: 32365353.
      Citations: 97     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. Cong Y, Ulasli M, Schepers H, Mauthe M, V'kovski P, Kriegenburg F, Thiel V, de Haan CAM, Reggiori F. Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle. J Virol. 2020 01 31; 94(4). PMID: 31776274.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    24. V'kovski P, Steiner S, Thiel V. Proximity Labeling for the Identification of Coronavirus-Host Protein Interactions. Methods Mol Biol. 2020; 2203:187-204. PMID: 32833213.
      Citations: 1     Fields:    Translation:AnimalsCells
    25. Zhao Y, Cheng J, Xu G, Thiel V, Zhang G. Successful establishment of a reverse genetic system for QX-type infectious bronchitis virus and technical improvement of the rescue procedure. Virus Res. 2019 10 15; 272:197726. PMID: 31430502.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    26. Jonsdottir HR, Marti S, Geerts D, Rodriguez R, Thiel V, Dijkman R. Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions. Viruses. 2019 08 13; 11(8). PMID: 31412613.
      Citations: 5     Fields:    Translation:HumansCells
    27. Contu L, Steiner S, Thiel V, Mühlemann O. The Role of Stress Granules and the Nonsense-mediated mRNA Decay Pathway in Antiviral Defence. Chimia (Aarau). 2019 May 29; 73(6):374-379. PMID: 31118119.
      Citations: 5     Fields:    Translation:Cells
    28. V'kovski P, Gerber M, Kelly J, Pfaender S, Ebert N, Braga Lagache S, Simillion C, Portmann J, Stalder H, Gaschen V, Bruggmann R, Stoffel MH, Heller M, Dijkman R, Thiel V. Determination of host proteins composing the microenvironment of coronavirus replicase complexes by proximity-labeling. Elife. 2019 01 11; 8. PMID: 30632963.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    29. García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S. The Small-Compound Inhibitor K22 Displays Broad Antiviral Activity against Different Members of the Family Flaviviridae and Offers Potential as a Panviral Inhibitor. Antimicrob Agents Chemother. 2018 11; 62(11). PMID: 30181371.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    30. Muth D, Corman VM, Roth H, Binger T, Dijkman R, Gottula LT, Gloza-Rausch F, Balboni A, Battilani M, Rihtaric D, Toplak I, Ameneiros RS, Pfeifer A, Thiel V, Drexler JF, Müller MA, Drosten C. Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission. Sci Rep. 2018 10 11; 8(1):15177. PMID: 30310104.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    31. Milewska A, Kindler E, Vkovski P, Zeglen S, Ochman M, Thiel V, Rajfur Z, Pyrc K. APOBEC3-mediated restriction of RNA virus replication. Sci Rep. 2018 04 13; 8(1):5960. PMID: 29654310.
      Citations: 33     Fields:    Translation:HumansCells
    32. Rappe JCF, de Wilde A, Di H, Müller C, Stalder H, V'kovski P, Snijder E, Brinton MA, Ziebuhr J, Ruggli N, Thiel V. Antiviral activity of K22 against members of the order Nidovirales. Virus Res. 2018 02 15; 246:28-34. PMID: 29337162.
      Citations: 5     Fields:    Translation:AnimalsCells
    33. Siddharta A, Pfaender S, Vielle NJ, Dijkman R, Friesland M, Becker B, Yang J, Engelmann M, Todt D, Windisch MP, Brill FH, Steinmann J, Steinmann J, Becker S, Alves MP, Pietschmann T, Eickmann M, Thiel V, Steinmann E. Virucidal Activity of World Health Organization-Recommended Formulations Against Enveloped Viruses, Including Zika, Ebola, and Emerging Coronaviruses. J Infect Dis. 2017 03 15; 215(6):902-906. PMID: 28453839.
      Citations: 65     Fields:    Translation:HumansCellsPHPublic Health
    34. Kindler E, Gil-Cruz C, Spanier J, Li Y, Wilhelm J, Rabouw HH, Züst R, Hwang M, V'kovski P, Stalder H, Marti S, Habjan M, Cervantes-Barragan L, Elliot R, Karl N, Gaughan C, van Kuppeveld FJ, Silverman RH, Keller M, Ludewig B, Bergmann CC, Ziebuhr J, Weiss SR, Kalinke U, Thiel V. Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication. PLoS Pathog. 2017 02; 13(2):e1006195. PMID: 28158275.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    35. Kindler E, Thiel V, Weber F. Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response. Adv Virus Res. 2016; 96:219-243. PMID: 27712625.
      Citations: 120     Fields:    Translation:HumansCells
    36. Corman VM, Eckerle I, Memish ZA, Liljander AM, Dijkman R, Jonsdottir H, Juma Ngeiywa KJ, Kamau E, Younan M, Al Masri M, Assiri A, Gluecks I, Musa BE, Meyer B, Müller MA, Hilali M, Bornstein S, Wernery U, Thiel V, Jores J, Drexler JF, Drosten C. Link of a ubiquitous human coronavirus to dromedary camels. Proc Natl Acad Sci U S A. 2016 08 30; 113(35):9864-9. PMID: 27528677.
      Citations: 48     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    37. Kindler E, Thiel V. SARS-CoV and IFN: Too Little, Too Late. Cell Host Microbe. 2016 Feb 10; 19(2):139-41. PMID: 26867172.
      Citations: 49     Translation:AnimalsCells
    38. Corman VM, Baldwin HJ, Tateno AF, Zerbinati RM, Annan A, Owusu M, Nkrumah EE, Maganga GD, Oppong S, Adu-Sarkodie Y, Vallo P, da Silva Filho LV, Leroy EM, Thiel V, van der Hoek L, Poon LL, Tschapka M, Drosten C, Drexler JF. Evidence for an Ancestral Association of Human Coronavirus 229E with Bats. J Virol. 2015 Dec; 89(23):11858-70. PMID: 26378164.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    39. Pas SD, Patel P, Reusken C, Domingo C, Corman VM, Drosten C, Dijkman R, Thiel V, Nowotny N, Koopmans MP, Niedrig M. First international external quality assessment of molecular diagnostics for Mers-CoV. J Clin Virol. 2015 Aug; 69:81-5. PMID: 26209385.
      Citations: 14     Fields:    Translation:HumansCells
    40. Mielech AM, Deng X, Chen Y, Kindler E, Wheeler DL, Mesecar AD, Thiel V, Perlman S, Baker SC. Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. J Virol. 2015 May; 89(9):4907-17. PMID: 25694594.
      Citations: 26     Fields:    Translation:AnimalsCells
    41. V'kovski P, Al-Mulla H, Thiel V, Neuman BW. New insights on the role of paired membrane structures in coronavirus replication. Virus Res. 2015 Apr 16; 202:33-40. PMID: 25550072.
      Citations: 13     Fields:    Translation:Cells
    42. Thiel V, Thiel HJ, Tekes G. Tackling feline infectious peritonitis via reverse genetics. Bioengineered. 2014; 5(6):396-400. PMID: 25482087.
      Citations: 7     Fields:    Translation:AnimalsCells
    43. Kindler E, Thiel V. To sense or not to sense viral RNA--essentials of coronavirus innate immune evasion. Curr Opin Microbiol. 2014 Aug; 20:69-75. PMID: 24908561.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    44. Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E. Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus. PLoS Pathog. 2014 May; 10(5):e1004166. PMID: 24874215.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    45. Al-Mulla HM, Turrell L, Smith NM, Payne L, Baliji S, Züst R, Thiel V, Baker SC, Siddell SG, Neuman BW. Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions. mBio. 2014 Apr 01; 5(2):e01107-13. PMID: 24692638.
      Citations: 19     Fields:    Translation:AnimalsCells
    46. Hamming OJ, Terczynska-Dyla E, Vieyres G, Dijkman R, Jørgensen SE, Akhtar H, Siupka P, Pietschmann T, Thiel V, Hartmann R. Interferon lambda 4 signals via the IFN? receptor to regulate antiviral activity against HCV and coronaviruses. EMBO J. 2013 Nov 27; 32(23):3055-65. PMID: 24169568.
      Citations: 84     Fields:    Translation:HumansCells
    47. Wang C, Sun X, Suo S, Ren Y, Li X, Herrler G, Thiel V, Ren X. Phages bearing affinity peptides to severe acute respiratory syndromes-associated coronavirus differentiate this virus from other viruses. J Clin Virol. 2013 Aug; 57(4):305-10. PMID: 23664850.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    48. Chai Q, Onder L, Scandella E, Gil-Cruz C, Perez-Shibayama C, Cupovic J, Danuser R, Sparwasser T, Luther SA, Thiel V, Rülicke T, Stein JV, Hehlgans T, Ludewig B. Maturation of lymph node fibroblastic reticular cells from myofibroblastic precursors is critical for antiviral immunity. Immunity. 2013 May 23; 38(5):1013-24. PMID: 23623380.
      Citations: 89     Fields:    Translation:AnimalsCells
    49. Bertram S, Dijkman R, Habjan M, Heurich A, Gierer S, Glowacka I, Welsch K, Winkler M, Schneider H, Hofmann-Winkler H, Thiel V, Pöhlmann S. TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium. J Virol. 2013 Jun; 87(11):6150-60. PMID: 23536651.
      Citations: 128     Fields:    Translation:HumansCells
    50. Raj VS, Mou H, Smits SL, Dekkers DH, Müller MA, Dijkman R, Muth D, Demmers JA, Zaki A, Fouchier RA, Thiel V, Drosten C, Rottier PJ, Osterhaus AD, Bosch BJ, Haagmans BL. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature. 2013 Mar 14; 495(7440):251-4. PMID: 23486063.
      Citations: 867     Fields:    Translation:HumansAnimalsCells
    51. Dijkman R, Jebbink MF, Koekkoek SM, Deijs M, Jónsdóttir HR, Molenkamp R, Ieven M, Goossens H, Thiel V, van der Hoek L. Isolation and characterization of current human coronavirus strains in primary human epithelial cell cultures reveal differences in target cell tropism. J Virol. 2013 Jun; 87(11):6081-90. PMID: 23427150.
      Citations: 71     Fields:    Translation:HumansCells
    52. Kindler E, Jónsdóttir HR, Muth D, Hamming OJ, Hartmann R, Rodriguez R, Geffers R, Fouchier RA, Drosten C, Müller MA, Dijkman R, Thiel V. Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential. mBio. 2013 Feb 19; 4(1):e00611-12. PMID: 23422412.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    53. Tekes G, Spies D, Bank-Wolf B, Thiel V, Thiel HJ. A reverse genetics approach to study feline infectious peritonitis. J Virol. 2012 Jun; 86(12):6994-8. PMID: 22491466.
      Citations: 15     Fields:    Translation:AnimalsCells
    54. Cervantes-Barragán L, Firner S, Bechmann I, Waisman A, Lahl K, Sparwasser T, Thiel V, Ludewig B. Regulatory T cells selectively preserve immune privilege of self-antigens during viral central nervous system infection. J Immunol. 2012 Apr 15; 188(8):3678-85. PMID: 22407917.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    55. van den Worm SH, Eriksson KK, Zevenhoven JC, Weber F, Züst R, Kuri T, Dijkman R, Chang G, Siddell SG, Snijder EJ, Thiel V, Davidson AD. Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination. PLoS One. 2012; 7(3):e32857. PMID: 22412934.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    56. Carbajo-Lozoya J, Müller MA, Kallies S, Thiel V, Drosten C, von Brunn A. Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506. Virus Res. 2012 Apr; 165(1):112-7. PMID: 22349148.
      Citations: 87     Fields:    Translation:HumansCells
    57. Cervantes-Barragan L, Lewis KL, Firner S, Thiel V, Hugues S, Reith W, Ludewig B, Reizis B. Plasmacytoid dendritic cells control T-cell response to chronic viral infection. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3012-7. PMID: 22315415.
      Citations: 96     Fields:    Translation:AnimalsCells
    58. Gil-Cruz C, Perez-Shibayama C, Firner S, Waisman A, Bechmann I, Thiel V, Cervantes-Barragan L, Ludewig B. T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating disease. Proc Natl Acad Sci U S A. 2012 Jan 24; 109(4):1233-8. PMID: 22232667.
      Citations: 11     Fields:    Translation:AnimalsCells
    59. Pfefferle S, Schöpf J, Kögl M, Friedel CC, Müller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Züst R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pöhlmann S, Haas J, Drosten C, von Brunn A. The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors. PLoS Pathog. 2011 Oct; 7(10):e1002331. PMID: 22046132.
      Citations: 196     Fields:    Translation:HumansAnimalsCells
    60. de Wilde AH, Zevenhoven-Dobbe JC, van der Meer Y, Thiel V, Narayanan K, Makino S, Snijder EJ, van Hemert MJ. Cyclosporin A inhibits the replication of diverse coronaviruses. J Gen Virol. 2011 Nov; 92(Pt 11):2542-2548. PMID: 21752960.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    61. Kuri T, Eriksson KK, Putics A, Züst R, Snijder EJ, Davidson AD, Siddell SG, Thiel V, Ziebuhr J, Weber F. The ADP-ribose-1''-monophosphatase domains of severe acute respiratory syndrome coronavirus and human coronavirus 229E mediate resistance to antiviral interferon responses. J Gen Virol. 2011 Aug; 92(Pt 8):1899-1905. PMID: 21525212.
      Citations: 54     Fields:    Translation:HumansCells
    62. Züst R, Cervantes-Barragan L, Habjan M, Maier R, Neuman BW, Ziebuhr J, Szretter KJ, Baker SC, Barchet W, Diamond MS, Siddell SG, Ludewig B, Thiel V. Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol. 2011 Feb; 12(2):137-43. PMID: 21217758.
      Citations: 341     Fields:    Translation:HumansAnimalsCells
    63. Daffis S, Szretter KJ, Schriewer J, Li J, Youn S, Errett J, Lin TY, Schneller S, Zust R, Dong H, Thiel V, Sen GC, Fensterl V, Klimstra WB, Pierson TC, Buller RM, Gale M, Shi PY, Diamond MS. 2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature. 2010 Nov 18; 468(7322):452-6. PMID: 21085181.
      Citations: 368     Fields:    Translation:HumansAnimalsCells
    64. Cervantes-Barragan L, Züst R, Maier R, Sierro S, Janda J, Levy F, Speiser D, Romero P, Rohrlich PS, Ludewig B, Thiel V. Dendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity. mBio. 2010 Sep 14; 1(4). PMID: 20844609.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    65. Tekes G, Hofmann-Lehmann R, Bank-Wolf B, Maier R, Thiel HJ, Thiel V. Chimeric feline coronaviruses that encode type II spike protein on type I genetic background display accelerated viral growth and altered receptor usage. J Virol. 2010 Feb; 84(3):1326-33. PMID: 19906918.
      Citations: 18     Fields:    Translation:AnimalsCells
    66. Roth-Cross JK, Stokes H, Chang G, Chua MM, Thiel V, Weiss SR, Gorbalenya AE, Siddell SG. Organ-specific attenuation of murine hepatitis virus strain A59 by replacement of catalytic residues in the putative viral cyclic phosphodiesterase ns2. J Virol. 2009 Apr; 83(8):3743-53. PMID: 19176619.
      Citations: 31     Fields:    Translation:AnimalsCells
    67. Cervantes-Barragán L, Kalinke U, Züst R, König M, Reizis B, López-Macías C, Thiel V, Ludewig B. Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection. J Immunol. 2009 Jan 15; 182(2):1099-106. PMID: 19124753.
      Citations: 65     Fields:    Translation:AnimalsCells
    68. Eriksson KK, Cervantes-Barragán L, Ludewig B, Thiel V. Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup. J Virol. 2008 Dec; 82(24):12325-34. PMID: 18922871.
      Citations: 75     Fields:    Translation:AnimalsCells
    69. Thiel V, Weber F. Interferon and cytokine responses to SARS-coronavirus infection. Cytokine Growth Factor Rev. 2008 Apr; 19(2):121-32. PMID: 18321765.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    70. Eriksson KK, Makia D, Thiel V. Generation of recombinant coronaviruses using vaccinia virus as the cloning vector and stable cell lines containing coronaviral replicon RNAs. Methods Mol Biol. 2008; 454:237-54. PMID: 19057873.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    71. Tekes G, Hofmann-Lehmann R, Stallkamp I, Thiel V, Thiel HJ. Genome organization and reverse genetic analysis of a type I feline coronavirus. J Virol. 2008 Feb; 82(4):1851-9. PMID: 18077720.
      Citations: 30     Fields:    Translation:AnimalsCells
    72. Züst R, Miller TB, Goebel SJ, Thiel V, Masters PS. Genetic interactions between an essential 3' cis-acting RNA pseudoknot, replicase gene products, and the extreme 3' end of the mouse coronavirus genome. J Virol. 2008 Feb; 82(3):1214-28. PMID: 18032506.
      Citations: 56     Fields:    Translation:AnimalsCells
    73. Züst R, Cervantes-Barragán L, Kuri T, Blakqori G, Weber F, Ludewig B, Thiel V. Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS Pathog. 2007 Aug 10; 3(8):e109. PMID: 17696607.
      Citations: 128     Fields:    Translation:HumansAnimalsCells
    74. Ziebuhr J, Schelle B, Karl N, Minskaia E, Bayer S, Siddell SG, Gorbalenya AE, Thiel V. Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication. J Virol. 2007 Apr; 81(8):3922-32. PMID: 17251282.
      Citations: 36     Fields:    Translation:HumansCells
    75. Dijkman R, Jebbink MF, Wilbrink B, Pyrc K, Zaaijer HL, Minor PD, Franklin S, Berkhout B, Thiel V, van der Hoek L. Human coronavirus 229E encodes a single ORF4 protein between the spike and the envelope genes. Virol J. 2006 Dec 28; 3:106. PMID: 17194306.
      Citations: 26     Fields:    Translation:HumansCells
    76. Cervantes-Barragan L, Züst R, Weber F, Spiegel M, Lang KS, Akira S, Thiel V, Ludewig B. Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon. Blood. 2007 Feb 01; 109(3):1131-7. PMID: 16985170.
      Citations: 197     Fields:    Translation:HumansAnimalsCells
    77. Eriksson KK, Makia D, Maier R, Ludewig B, Thiel V. Towards a coronavirus-based HIV multigene vaccine. Clin Dev Immunol. 2006 Jun-Dec; 13(2-4):353-60. PMID: 17162377.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    78. Schelle B, Karl N, Ludewig B, Siddell SG, Thiel V. Nucleocapsid protein expression facilitates coronavirus replication. Adv Exp Med Biol. 2006; 581:43-8. PMID: 17037502.
      Citations: 6     Fields:    Translation:Cells
    79. Eriksson KK, Makia D, Maier R, Cervantes L, Ludewig B, Thiel V. Efficient transduction of dendritic cells using coronavirus-based vectors. Adv Exp Med Biol. 2006; 581:203-6. PMID: 17037531.
      Citations: 2     Fields:    Translation:AnimalsCells
    80. Scandella E, Eriksson KK, Hertzig T, Drosten C, Chen L, Gui C, Luo X, Shen J, Shen X, Siddell SG, Ludewig B, Jiang H, Günther S, Thiel V. Identification and evaluation of coronavirus replicase inhibitors using a replicon cell line. Adv Exp Med Biol. 2006; 581:609-13. PMID: 17037607.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    81. Sawicki SG, Sawicki DL, Younker D, Meyer Y, Thiel V, Stokes H, Siddell SG. Functional and genetic analysis of coronavirus replicase-transcriptase proteins. PLoS Pathog. 2005 Dec; 1(4):e39. PMID: 16341254.
      Citations: 81     Fields:    Translation:Cells
    82. Schelle B, Karl N, Ludewig B, Siddell SG, Thiel V. Selective replication of coronavirus genomes that express nucleocapsid protein. J Virol. 2005 Jun; 79(11):6620-30. PMID: 15890900.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    83. Chen L, Gui C, Luo X, Yang Q, Günther S, Scandella E, Drosten C, Bai D, He X, Ludewig B, Chen J, Luo H, Yang Y, Yang Y, Zou J, Thiel V, Chen K, Shen J, Shen X, Jiang H. Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro. J Virol. 2005 Jun; 79(11):7095-103. PMID: 15890949.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    84. Coley SE, Lavi E, Sawicki SG, Fu L, Schelle B, Karl N, Siddell SG, Thiel V. Recombinant mouse hepatitis virus strain A59 from cloned, full-length cDNA replicates to high titers in vitro and is fully pathogenic in vivo. J Virol. 2005 Mar; 79(5):3097-106. PMID: 15709029.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    85. Thiel V, Siddell SG. Reverse genetics of coronaviruses using vaccinia virus vectors. Curr Top Microbiol Immunol. 2005; 287:199-227. PMID: 15609513.
      Citations: 20     Fields:    Translation:HumansCells
    86. Ivanov KA, Hertzig T, Rozanov M, Bayer S, Thiel V, Gorbalenya AE, Ziebuhr J. Major genetic marker of nidoviruses encodes a replicative endoribonuclease. Proc Natl Acad Sci U S A. 2004 Aug 24; 101(34):12694-9. PMID: 15304651.
      Citations: 147     Fields:    Translation:HumansCells
    87. Ivanov KA, Thiel V, Dobbe JC, van der Meer Y, Snijder EJ, Ziebuhr J. Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase. J Virol. 2004 Jun; 78(11):5619-32. PMID: 15140959.
      Citations: 176     Fields:    Translation:AnimalsCells
    88. Hertzig T, Scandella E, Schelle B, Ziebuhr J, Siddell SG, Ludewig B, Thiel V. Rapid identification of coronavirus replicase inhibitors using a selectable replicon RNA. J Gen Virol. 2004 Jun; 85(Pt 6):1717-1725. PMID: 15166457.
      Citations: 33     Fields:    Translation:AnimalsCells
    89. Thiel V, Karl N, Schelle B, Disterer P, Klagge I, Siddell SG. Multigene RNA vector based on coronavirus transcription. J Virol. 2003 Sep; 77(18):9790-8. PMID: 12941887.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    90. Thiel V, Ivanov KA, Putics Á, Hertzig T, Schelle B, Bayer S, Weißbrich B, Snijder EJ, Rabenau H, Doerr HW, Gorbalenya AE, Ziebuhr J. Mechanisms and enzymes involved in SARS coronavirus genome expression. J Gen Virol. 2003 Sep; 84(Pt 9):2305-2315. PMID: 12917450.
      Citations: 374     Fields:    Translation:Cells
    91. Snijder EJ, Bredenbeek PJ, Dobbe JC, Thiel V, Ziebuhr J, Poon LL, Guan Y, Rozanov M, Spaan WJ, Gorbalenya AE. Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol. 2003 Aug 29; 331(5):991-1004. PMID: 12927536.
      Citations: 603     Fields:    Translation:HumansAnimalsCells
    92. Thiel V, Herold J, Siddell SG. Long distance reverse-transcription PCR. Methods Mol Biol. 2002; 192:59-66. PMID: 12494637.
      Citations: 1     Fields:    Translation:HumansCells
    93. Casais R, Thiel V, Siddell SG, Cavanagh D, Britton P. Reverse genetics system for the avian coronavirus infectious bronchitis virus. J Virol. 2001 Dec; 75(24):12359-69. PMID: 11711626.
      Citations: 120     Fields:    Translation:AnimalsCells
    94. Thiel V, Herold J, Schelle B, Siddell SG. Viral replicase gene products suffice for coronavirus discontinuous transcription. J Virol. 2001 Jul; 75(14):6676-81. PMID: 11413334.
      Citations: 67     Fields:    Translation:Cells
    95. Ziebuhr J, Thiel V, Gorbalenya AE. The autocatalytic release of a putative RNA virus transcription factor from its polyprotein precursor involves two paralogous papain-like proteases that cleave the same peptide bond. J Biol Chem. 2001 Aug 31; 276(35):33220-32. PMID: 11431476.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    96. Thiel V, Herold J, Schelle B, Siddell SG. Infectious RNA transcribed in vitro from a cDNA copy of the human coronavirus genome cloned in vaccinia virus. J Gen Virol. 2001 Jun; 82(Pt 6):1273-1281. PMID: 11369870.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
    97. Siddell S, Sawicki D, Meyer Y, Thiel V, Sawicki S. Identification of the mutations responsible for the phenotype of three MHV RNA-negative ts mutants. Adv Exp Med Biol. 2001; 494:453-8. PMID: 11774507.
      Citations: 13     Fields:    Translation:AnimalsCells
    98. Jendrach M, Thiel V, Siddell S. Characterization of an internal ribosome entry site within mRNA 5 of murine hepatitis virus. Arch Virol. 1999; 144(5):921-33. PMID: 10416375.
      Citations: 17     Fields:    Translation:AnimalsCells
    99. Herold J, Gorbalenya AE, Thiel V, Schelle B, Siddell SG. Proteolytic processing at the amino terminus of human coronavirus 229E gene 1-encoded polyproteins: identification of a papain-like proteinase and its substrate. J Virol. 1998 Feb; 72(2):910-8. PMID: 9444982.
      Citations: 35     Fields:    Translation:HumansCells
    100. Thiel V, Siddell SG, Herold J. Replication and transcription of HCV 229E replicons. p6. Adv Exp Med Biol. 1998; 440:109-13. PMID: 9782271.
      Citations: 5     Fields:    Translation:HumansCells
    101. Herold J, Thiel V, Siddell SG. Characterization of a papain-like cysteine-proteinase encoded by gene 1 of the human coronavirus HCV 229E. Adv Exp Med Biol. 1998; 440:141-7. PMID: 9782276.
      Citations: 2     Fields:    Translation:HumansCells
    102. Herold J, Thiel V, Siddell SG. A strategy for the generation of infectious RNAs and autonomously replicating RNAs based on the HCV 229E genome. Adv Exp Med Biol. 1998; 440:265-8. PMID: 9782291.
      Citations:    Fields:    Translation:HumansCells
    103. Thiel V, Herold J, Siddell SG. Long distance RT-PCRs of human coronavirus 229E RNA. Adv Exp Med Biol. 1998; 440:269-73. PMID: 9782292.
      Citations:    Fields:    Translation:HumansCells
    104. Thiel V, Rashtchian A, Herold J, Schuster DM, Guan N, Siddell SG. Effective amplification of 20-kb DNA by reverse transcription PCR. Anal Biochem. 1997 Oct 01; 252(1):62-70. PMID: 9324942.
      Citations: 16     Fields:    Translation:HumansCells
    105. Thiel V, Siddell S. Translation of the MHV sM protein is mediated by the internal entry of ribosomes on mRNA 5. Adv Exp Med Biol. 1995; 380:311-5. PMID: 8830499.
      Citations: 1     Fields:    Translation:AnimalsCells
    106. Thiel V, Siddell SG. Internal ribosome entry in the coding region of murine hepatitis virus mRNA 5. J Gen Virol. 1994 Nov; 75 ( Pt 11):3041-6. PMID: 7964613.
      Citations: 37     Fields:    Translation:AnimalsCells
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