Insulin Receptor Substrate Proteins

"Insulin Receptor Substrate Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
MeSH information
A structurally-related group of signaling proteins that are phosphorylated by the INSULIN RECEPTOR PROTEIN-TYROSINE KINASE. The proteins share an N-terminal PLECKSTRIN HOMOLOGY DOMAIN, a phosphotyrosine-binding domain that interacts with the phosphorylated INSULIN RECEPTOR, and a C-terminal TYROSINE-rich domain. Upon tyrosine phosphorylation, insulin receptor substrate proteins interact with specific SH2 DOMAIN containing proteins that are involved in insulin receptor signaling.


Publications
This graph shows the total number of publications written about "Insulin Receptor Substrate Proteins" by people in this website by year, and whether "Insulin Receptor Substrate Proteins" was a major or minor topic of these publications.
Bar chart showing 12 publications over 6 distinct years, with a maximum of 5 publications in 2017
To see the data from this visualization as text, click here.
_
Top Journals expand description