Protein Inhibitors of Activated STAT
"Protein Inhibitors of Activated STAT" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of signal transducers and activators of transcription.
Descriptor ID |
D050828
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MeSH Number(s) |
D12.644.360.024.319 D12.776.157.057.124 D12.776.476.024.402
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Protein Inhibitors of Activated STAT".
Below are MeSH descriptors whose meaning is more specific than "Protein Inhibitors of Activated STAT".
This graph shows the total number of publications written about "Protein Inhibitors of Activated STAT" by people in this website by year, and whether "Protein Inhibitors of Activated STAT" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Inhibitors of Activated STAT" by people in Profiles.
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Epithelial cell-specific loss of function of Miz1 causes a spontaneous COPD-like phenotype and up-regulates Ace2 expression in mice. Sci Adv. 2020 08; 6(33):eabb7238.
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Increased expression of mir-301a in PBMCs of patients with relapsing-remitting multiple sclerosis is associated with reduced NKRF and PIAS3 expression levels and disease activity. J Neuroimmunol. 2018 12 15; 325:79-86.
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Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia. Sci Rep. 2017 09 25; 7(1):12262.
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BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):11294-9.
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Human parvovirus B19 NS1 protein modulates inflammatory signaling by activation of STAT3/PIAS3 in human endothelial cells. J Virol. 2008 Aug; 82(16):7942-52.