"A Kinase Anchor Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.
Descriptor ID |
D054758
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MeSH Number(s) |
D12.644.360.024.065 D12.776.157.057.003 D12.776.476.024.069
|
Concept/Terms |
A Kinase Anchor Proteins- A Kinase Anchor Proteins
- Protein Kinase A Anchor Proteins
- A-Kinase Anchor Proteins
- Anchor Proteins, A-Kinase
|
Below are MeSH descriptors whose meaning is more general than "A Kinase Anchor Proteins".
Below are MeSH descriptors whose meaning is more specific than "A Kinase Anchor Proteins".
This graph shows the total number of publications written about "A Kinase Anchor Proteins" by people in this website by year, and whether "A Kinase Anchor Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2016 | 0 | 2 | 2 |
2017 | 1 | 2 | 3 |
2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "A Kinase Anchor Proteins" by people in Profiles.
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS One. 2018; 13(7):e0197561.
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Akap1 Regulates Vascular Function and Endothelial Cells Behavior. Hypertension. 2018 03; 71(3):507-517.
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Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. Elife. 2017 10 02; 6.
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Loss of type 9 adenylyl cyclase triggers reduced phosphorylation of Hsp20 and diastolic dysfunction. Sci Rep. 2017 07 17; 7(1):5522.
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Local protein kinase A action proceeds through intact holoenzymes. Science. 2017 06 23; 356(6344):1288-1293.
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Gene-Targeted Analysis of Clinically Diagnosed Long QT Russian Families. Int Heart J. 2017 Feb 07; 58(1):81-87.
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Crystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activation. J Gen Virol. 2016 Apr; 97(4):880-886.
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Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene. mBio. 2014 Jul 01; 5(4):e01312-14.