"Thioredoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hydrogen-donating proteins that participates in a variety of biochemical reactions including ribonucleotide reduction and reduction of PEROXIREDOXINS. Thioredoxin is oxidized from a dithiol to a disulfide when acting as a reducing cofactor. The disulfide form is then reduced by NADPH in a reaction catalyzed by THIOREDOXIN REDUCTASE.
| Descriptor ID |
D013879
|
| MeSH Number(s) |
D12.776.915
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thioredoxins".
Below are MeSH descriptors whose meaning is more specific than "Thioredoxins".
This graph shows the total number of publications written about "Thioredoxins" by people in this website by year, and whether "Thioredoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 2 | 5 |
| 2018 | 5 | 3 | 8 |
| 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thioredoxins" by people in Profiles.
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Overview of thioredoxin system and targeted therapies for acute leukemia. Mitochondrion. 2019 07; 47:38-46.
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The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses. Eur J Immunol. 2019 05; 49(5):709-723.
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The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background. Nat Commun. 2018 12 04; 9(1):5158.
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Compound kushen injection suppresses human acute myeloid leukaemia by regulating the Prdxs/ROS/Trx1 signalling pathway. J Exp Clin Cancer Res. 2018 Nov 19; 37(1):277.
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Geranylgeranylacetone blocks the reinstatement of morphine-conditioned place preference. Neuropharmacology. 2018 12; 143:63-70.
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Analysis of IL17A and IL21 Expression in the Small Intestine of Celiac Disease Patients and Correlation with Circulating Thioredoxin Level. Genet Test Mol Biomarkers. 2018 Sep; 22(9):518-525.
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Sex-Specific Response of Caenorhabditis elegans to Methylmercury Toxicity. Neurotox Res. 2019 Jan; 35(1):208-216.
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The cytoplasmic thioredoxin system in Caenorhabditis elegans affords protection from methylmercury in an age-specific manner. Neurotoxicology. 2018 09; 68:189-202.
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Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice. Free Radic Biol Med. 2018 08 20; 124:380-387.
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The role of the thioredoxin/thioredoxin reductase system in the metabolic syndrome: towards a possible prognostic marker? Cell Mol Life Sci. 2018 05; 75(9):1567-1586.