"LIM Domain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.
| Descriptor ID |
D060588
|
| MeSH Number(s) |
D12.776.512
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "LIM Domain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM Domain Proteins".
This graph shows the total number of publications written about "LIM Domain Proteins" by people in this website by year, and whether "LIM Domain Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 3 | 0 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "LIM Domain Proteins" by people in Profiles.
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FHL1 is a major host factor for chikungunya virus infection. Nature. 2019 10; 574(7777):259-263.
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LIM and SH3 protein 1 regulates cell growth and chemosensitivity of human glioblastoma via the PI3K/AKT pathway. BMC Cancer. 2018 Jul 06; 18(1):722.
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Reduced atherosclerosis lesion size, inflammatory response in miR-150 knockout mice via macrophage effects. J Lipid Res. 2018 04; 59(4):658-669.
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In vitro and in silico validation of CA3 and FHL1 downregulation in oral cancer. BMC Cancer. 2018 02 17; 18(1):193.
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Profiles of differentially expressed genes and overexpression of NEBL indicates a positive prognosis in patients with colorectal cancer. Mol Med Rep. 2018 Feb; 17(2):3028-3034.
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Cysteine and glycine-rich protein 2 (CSRP2) transcript levels correlate with leukemia relapse and leukemia-free survival in adults with B-cell acute lymphoblastic leukemia and normal cytogenetics. Oncotarget. 2017 May 30; 8(22):35984-36000.
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LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis. Nat Commun. 2017 04 24; 8:15059.