"Protein Stability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The ability of a protein to retain its structural conformation or its activity when subjected to physical or chemical manipulations.
| Descriptor ID |
D055550
|
| MeSH Number(s) |
G02.111.700
|
| Concept/Terms |
Protein Stability- Protein Stability
- Protein Stabilities
- Stabilities, Protein
- Stability, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Stability".
Below are MeSH descriptors whose meaning is more specific than "Protein Stability".
This graph shows the total number of publications written about "Protein Stability" by people in this website by year, and whether "Protein Stability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 4 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 56 | 57 |
| 2018 | 2 | 31 | 33 |
| 2019 | 0 | 11 | 11 |
| 2020 | 0 | 12 | 12 |
| 2021 | 1 | 4 | 5 |
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Below are the most recent publications written about "Protein Stability" by people in Profiles.
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Protease cleavage of RNF20 facilitates coronavirus replication via stabilization of SREBP1. Proc Natl Acad Sci U S A. 2021 09 14; 118(37).
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SARS-CoV-2 Variants Are Selecting for Spike Protein Mutations That Increase Protein Stability. J Chem Inf Model. 2021 09 27; 61(9):4152-4155.
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[Induced degradation of proteins by PROTACs and other strategies: towards promising drugs]. Biol Aujourdhui. 2021; 215(1-2):25-43.
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Molecular Dynamics Studies on the Structural Characteristics for the Stability Prediction of SARS-CoV-2. Int J Mol Sci. 2021 Aug 13; 22(16).
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Plant-Produced Glycosylated and In Vivo Deglycosylated Receptor Binding Domain Proteins of SARS-CoV-2 Induce Potent Neutralizing Responses in Mice. Viruses. 2021 08 12; 13(8).
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Dimethyl sulfoxide reduces the stability but enhances catalytic activity of the main SARS-CoV-2 protease 3CLpro. FASEB J. 2021 08; 35(8):e21774.
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Transthyretin: From Structural Stability to Osteoarticular and Cardiovascular Diseases. Cells. 2021 07 13; 10(7).
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SARS-CoV-2 Spike Protein Stabilized in the Closed State Induces Potent Neutralizing Responses. J Virol. 2021 07 12; 95(15):e0020321.
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Effect of clinical isolate or cleavage site mutations in the SARS-CoV-2 spike protein on protein stability, cleavage, and cell-cell fusion. J Biol Chem. 2021 07; 297(1):100902.
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Increased elastase sensitivity and decreased intramolecular interactions in the more transmissible 501Y.V1 and 501Y.V2 SARS-CoV-2 variants' spike protein-an in silico analysis. PLoS One. 2021; 16(5):e0251426.