"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
|
| MeSH Number(s) |
E05.196.080 G02.111.084 G02.111.570.120.309
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 10 | 10 |
| 2018 | 0 | 3 | 3 |
| 2020 | 0 | 3 | 3 |
| 2021 | 0 | 5 | 5 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry. Pharmacol Res. 2021 10; 172:105820.
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COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria. Blood. 2021 07 01; 137(26):3670-3673.
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SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2. Cell. 2021 07 22; 184(15):3936-3948.e10.
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Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein. Cell. 2021 04 29; 184(9):2316-2331.e15.
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SARS-CoV-2 D614G spike mutation increases entry efficiency with enhanced ACE2-binding affinity. Nat Commun. 2021 02 08; 12(1):848.
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Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2. Nat Commun. 2021 02 05; 12(1):837.
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A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19. SLAS Discov. 2021 06; 26(5):620-627.
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Cell membrane chromatography for the analysis of the interaction between chloroquine and hydroxychloroquine with ACE2 receptors. J Chromatogr B Analyt Technol Biomed Life Sci. 2021 Jan 01; 1162:122469.
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Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2. Science. 2020 09 04; 369(6508):1261-1265.
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Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 08; 584(7821):443-449.