"Protein Multimerization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.
| Descriptor ID |
D055503
|
| MeSH Number(s) |
G02.111.694
|
| Concept/Terms |
Protein Multimerization- Protein Multimerization
- Multimerization, Protein
- Protein Multimer Assembly
- Assembly, Protein Multimer
- Multimer Assembly, Protein
|
Below are MeSH descriptors whose meaning is more general than "Protein Multimerization".
Below are MeSH descriptors whose meaning is more specific than "Protein Multimerization".
This graph shows the total number of publications written about "Protein Multimerization" by people in this website by year, and whether "Protein Multimerization" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 1 | 3 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 7 | 9 |
| 2017 | 19 | 63 | 82 |
| 2018 | 19 | 38 | 57 |
| 2019 | 3 | 13 | 16 |
| 2020 | 1 | 17 | 18 |
| 2021 | 3 | 9 | 12 |
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Below are the most recent publications written about "Protein Multimerization" by people in Profiles.
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Structure of the multiple functional domains from coronavirus nonstructural protein 3. Emerg Microbes Infect. 2021 Dec; 10(1):66-80.
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Single-dose immunisation with a multimerised SARS-CoV-2 receptor binding domain (RBD) induces an enhanced and protective response in mice. FEBS Lett. 2021 09; 595(18):2323-2340.
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Regulation of the Dimerization and Activity of SARS-CoV-2 Main Protease through Reversible Glutathionylation of Cysteine 300. mBio. 2021 08 31; 12(4):e0209421.
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A distinct ssDNA/RNA binding interface in the Nsp9 protein from SARS-CoV-2. Proteins. 2022 01; 90(1):176-185.
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Structural characterisation of inhibitory and non-inhibitory MMP-9-TIMP-1 complexes and implications for regulatory mechanisms of MMP-9. Sci Rep. 2021 06 28; 11(1):13376.
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Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease. Structure. 2021 08 05; 29(8):823-833.e5.
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Assessment of protein-protein interfaces in cryo-EM derived assemblies. Nat Commun. 2021 06 07; 12(1):3399.
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A Trimeric Hydrophobic Zipper Mediates the Intramembrane Assembly of SARS-CoV-2 Spike. J Am Chem Soc. 2021 06 16; 143(23):8543-8546.
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Comparative protein structure network analysis on 3CLpro from SARS-CoV-1 and SARS-CoV-2. Proteins. 2021 09; 89(9):1216-1225.
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Implementing a method for engineering multivalency to substantially enhance binding of clinical trial anti-SARS-CoV-2 antibodies to wildtype spike and variants of concern proteins. Sci Rep. 2021 05 18; 11(1):10475.