"DNA Repair" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.
| Descriptor ID |
D004260
|
| MeSH Number(s) |
G02.111.222 G05.219
|
| Concept/Terms |
Base Excision Repair- Base Excision Repair
- Base Excision Repairs
- Excision Repair, Base
- Repair, Base Excision
- Repairs, Base Excision
|
Below are MeSH descriptors whose meaning is more general than "DNA Repair".
Below are MeSH descriptors whose meaning is more specific than "DNA Repair".
This graph shows the total number of publications written about "DNA Repair" by people in this website by year, and whether "DNA Repair" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 9 | 20 | 29 |
| 2018 | 10 | 21 | 31 |
| 2019 | 4 | 3 | 7 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Repair" by people in Profiles.
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Cockayne Syndrome Group B (CSB): The Regulatory Framework Governing the Multifunctional Protein and Its Plausible Role in Cancer. Cells. 2021 04 10; 10(4).
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ADP-ribosylhydrolases: from DNA damage repair to COVID-19. J Zhejiang Univ Sci B. 2021 Jan 15; 22(1):21-30.
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[APOBEC3s: history of an antiviral and mutagenic protein family]. Virologie (Montrouge). 2020 12 01; 24(6):381-418.
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Are night shift workers at an increased risk for COVID-19? Med Hypotheses. 2020 Nov; 144:110147.
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High Fidelity Deep Sequencing Reveals No Effect of ATM, ATR, and DNA-PK Cellular DNA Damage Response Pathways on Adenovirus Mutation Rate. Viruses. 2019 10 11; 11(10).
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DNA damage response and repair in ovarian cancer: Potential targets for therapeutic strategies. DNA Repair (Amst). 2019 08; 80:59-84.
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Alterations in DNA Damage Repair Genes in Primary Liver Cancer. Clin Cancer Res. 2019 08 01; 25(15):4701-4711.
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The response to the DNA damaging agent methyl methanesulfonate in a fungal plant pathogen. Fungal Biol. 2019 05; 123(5):408-422.
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Targeting DNA Repair Defects for Precision Medicine in Prostate Cancer. Curr Oncol Rep. 2019 03 27; 21(5):42.
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Platinum salts in the treatment of BRCA-associated breast cancer: A true targeted chemotherapy? Crit Rev Oncol Hematol. 2019 Mar; 135:66-75.