"Complement Factor D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serum protein which is important in the ALTERNATIVE COMPLEMENT ACTIVATION PATHWAY. This enzyme cleaves the COMPLEMENT C3B-bound COMPLEMENT FACTOR B to form C3bBb which is ALTERNATIVE PATHWAY C3 CONVERTASE.
| Descriptor ID |
D011416
|
| MeSH Number(s) |
D08.811.277.300.450 D08.811.277.656.300.760.200 D08.811.277.656.959.350.200 D12.776.124.486.274.045.450
|
| Concept/Terms |
Complement Factor D- Complement Factor D
- Factor D, Complement
- C3PAse
- Complement Protein D
- Protein D, Complement
- GBGase
- Proactivator Convertase
- Convertase, Proactivator
- Properdin Factor D
- Factor D, Properdin
- C3 Proactivator Convertase
- Convertase, C3 Proactivator
- Adipsin
- C3 Convertase Activator
- Activator, C3 Convertase
- Convertase Activator, C3
- D Component of Complement
- Complement D Component
- 28 kDa Protein, Adipocyte
- C3PA Convertase
- Convertase, C3PA
- Factor D
|
Below are MeSH descriptors whose meaning is more general than "Complement Factor D".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor D".
This graph shows the total number of publications written about "Complement Factor D" by people in this website by year, and whether "Complement Factor D" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Complement Factor D" by people in Profiles.
-
COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria. Blood. 2021 07 01; 137(26):3670-3673.
-
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition. Blood. 2020 10 29; 136(18):2080-2089.
-
Targeting complement activation in COVID-19. Blood. 2020 10 29; 136(18):2000-2001.
-
The utility of complement assays in clinical immunology: A comprehensive review. J Autoimmun. 2018 12; 95:191-200.