"Tryptases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of neutral serine proteases with TRYPSIN-like activity. Tryptases are primarily found in the SECRETORY GRANULES of MAST CELLS and are released during mast cell degranulation.
Descriptor ID |
D053802
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MeSH Number(s) |
D08.811.277.656.300.760.902 D08.811.277.656.959.350.902
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tryptases".
Below are MeSH descriptors whose meaning is more specific than "Tryptases".
This graph shows the total number of publications written about "Tryptases" by people in this website by year, and whether "Tryptases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 1 | 2 | 3 |
2018 | 2 | 6 | 8 |
2019 | 3 | 2 | 5 |
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Below are the most recent publications written about "Tryptases" by people in Profiles.
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Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial. Lancet Respir Med. 2021 11; 9(11):1299-1312.
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Delving Into COVID-19 Vaccination-Induced Anaphylaxis: Are mRNA Vaccines Safe in Mast Cell Disorders? J Investig Allergol Clin Immunol. 2021 Apr 20; 31(2):193-195.
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Detection of KIT D816V mutation in patients with severe anaphylaxis and normal basal tryptase-first data from the Anaphylaxis Registry (NORA). J Allergy Clin Immunol. 2019 11; 144(5):1448-1450.e1.
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Plasma histamine elevation in a large cohort of sickle cell disease patients. Br J Haematol. 2019 07; 186(1):125-129.
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Progenitor mast cells and tryptase in Q fever. Comp Immunol Microbiol Infect Dis. 2019 Jun; 64:159-162.
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Mast cell tryptase - Marker and maker of cardiovascular diseases. Pharmacol Ther. 2019 07; 199:91-110.
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Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome. J Allergy Clin Immunol Pract. 2019 04; 7(4):1125-1133.e1.
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Emergency Management of Anaphylaxis Due to an Unknown Trigger: An 8-Year Follow-Up Study in Canada. J Allergy Clin Immunol Pract. 2019 04; 7(4):1166-1173.e1.
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Potential Role of Cytochrome c and Tryptase in Psoriasis and Psoriatic Arthritis Pathogenesis: Focus on Resistance to Apoptosis and Oxidative Stress. Front Immunol. 2018; 9:2363.
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The Italian Mastocytosis Registry: 6-year experience from a hospital-based registry. Future Oncol. 2018 11; 14(26):2713-2723.