"Syk Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
| Descriptor ID |
D000072377
|
| MeSH Number(s) |
D08.811.913.696.620.682.725.650 D12.644.360.900 D12.776.476.913
|
| Concept/Terms |
Syk Kinase- Syk Kinase
- Kinase, Syk
- SYK Tyrosine Kinase
- Kinase, SYK Tyrosine
- Tyrosine Kinase, SYK
- Spleen Tyrosine Kinase
- Kinase, Spleen Tyrosine
- Tyrosine Kinase, Spleen
|
Below are MeSH descriptors whose meaning is more general than "Syk Kinase".
Below are MeSH descriptors whose meaning is more specific than "Syk Kinase".
This graph shows the total number of publications written about "Syk Kinase" by people in this website by year, and whether "Syk Kinase" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 2 | 2 |
| 2018 | 3 | 3 | 6 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Syk Kinase" by people in Profiles.
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Immune thrombocytopenia: options and new perspectives. Blood Coagul Fibrinolysis. 2021 Oct 01; 32(7):427-433.
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Complement activation and increased expression of Syk, mucin-1 and CaMK4 in kidneys of patients with COVID-19. Clin Immunol. 2021 08; 229:108795.
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Repurposing Fostamatinib to Combat SARS-CoV-2-Induced Acute Lung Injury. Cell Rep Med. 2020 11 17; 1(8):100145.
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Three Novel Players: PTK2B, SYK, and TNFRSF21 Were Identified to Be Involved in the Regulation of Bovine Mastitis Susceptibility via GWAS and Post-transcriptional Analysis. Front Immunol. 2019; 10:1579.
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Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces. Int J Mol Sci. 2019 Jun 07; 20(11).
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Butyrate-Induced In Vitro Colonocyte Differentiation Network Model Identifies ITGB1, SYK, CDKN2A, CHAF1A, and LRP1 as the Prognostic Markers for Colorectal Cancer Recurrence. Nutr Cancer. 2019; 71(2):257-271.
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New biologics in the treatment of urticaria. Curr Opin Allergy Clin Immunol. 2018 10; 18(5):425-431.
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Role of the Spleen Tyrosine Kinase Pathway in Driving Inflammation in IgA Nephropathy. Semin Nephrol. 2018 09; 38(5):496-503.
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Cryptotanshinone inhibits IgE-mediated degranulation through inhibition of spleen tyrosine kinase and tyrosine-protein kinase phosphorylation in mast cells. Mol Med Rep. 2018 Jul; 18(1):1095-1103.
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SYK Inhibition Induces Apoptosis in Germinal Center-Like B Cells by Modulating the Antiapoptotic Protein Myeloid Cell Leukemia-1, Affecting B-Cell Activation and Antibody Production. Front Immunol. 2018; 9:787.