"Cyclins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They generally function as ENZYME ACTIVATORS that drive the CELL CYCLE through transitions between phases. A subset of cyclins may also function as transcriptional regulators.
| Descriptor ID |
D016213
|
| MeSH Number(s) |
D12.644.360.262 D12.776.167.218 D12.776.476.262
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclins".
Below are MeSH descriptors whose meaning is more specific than "Cyclins".
This graph shows the total number of publications written about "Cyclins" by people in this website by year, and whether "Cyclins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 3 | 4 |
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Below are the most recent publications written about "Cyclins" by people in Profiles.
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PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3. J Drug Target. 2019 04; 27(4):460-465.
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The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression. Elife. 2018 08 22; 7.
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Cyclin E2-CDK2 mediates SAMHD1 phosphorylation to abrogate its restriction of HBV replication in hepatoma cells. FEBS Lett. 2018 06; 592(11):1893-1904.
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EDAG promotes the expansion and survival of human CD34+ cells. PLoS One. 2018; 13(1):e0190794.
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Investigating CCNF mutations in a Taiwanese cohort with amyotrophic lateral sclerosis. Neurobiol Aging. 2018 02; 62:243.e1-243.e6.
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Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line. Cell Cycle. 2017; 16(21):2086-2099.
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Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochem J. 2017 02 20; 474(5):699-713.
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Re-expression of cell cycle markers in aged neurons and muscles: Whether cells should divide or die? Biochim Biophys Acta Mol Basis Dis. 2017 01; 1863(1):324-336.
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G1 phase cell cycle arrest induced by SARS-CoV 3a protein via the cyclin D3/pRb pathway. Am J Respir Cell Mol Biol. 2007 Jul; 37(1):9-19.
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SARS coronavirus 7a protein blocks cell cycle progression at G0/G1 phase via the cyclin D3/pRb pathway. Virology. 2006 Mar 01; 346(1):74-85.