Monomeric GTP-Binding Proteins
"Monomeric GTP-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of monomeric, low molecular weight (20-25 kDa) GTP-binding proteins that regulate a variety of intracellular processes. The GTP bound form of the protein is active and limited by its inherent GTPase activity, which is controlled by an array of GTPase activators, GDP dissociation inhibitors, and guanine nucleotide exchange factors. This enzyme was formerly listed as EC 3.6.1.47
| Descriptor ID |
D020559
|
| MeSH Number(s) |
D08.811.277.040.330.300.400 D12.644.360.525 D12.776.157.325.515 D12.776.476.525
|
| Concept/Terms |
Monomeric GTP-Binding Proteins- Monomeric GTP-Binding Proteins
- Monomeric GTP Binding Proteins
- Small GTPases
- GTPases, Small
- Monomeric G-Proteins
- Monomeric G Proteins
- Small G-Proteins
- G-Proteins, Small
- Small G Proteins
- G-Proteins, Monomeric
- G Proteins, Monomeric
- GTP-Binding Proteins, Monomeric
- GTP Binding Proteins, Monomeric
ras-Related GTPases- ras-Related GTPases
- GTPases, ras-Related
- ras Related GTPases
- ras-Related GTP-Binding Proteins
- GTP-Binding Proteins, ras-Related
- Proteins, ras-Related GTP-Binding
- ras Related GTP Binding Proteins
- ras-Related G-Proteins
- G-Proteins, ras-Related
- ras Related G Proteins
|
Below are MeSH descriptors whose meaning is more general than "Monomeric GTP-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Monomeric GTP-Binding Proteins".
This graph shows the total number of publications written about "Monomeric GTP-Binding Proteins" by people in this website by year, and whether "Monomeric GTP-Binding Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 2 | 4 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Monomeric GTP-Binding Proteins" by people in Profiles.
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Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis. JCI Insight. 2019 03 07; 5.
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Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor-Initiating Stem Cell-Like Cells Resistant to mTORC1 Inhibition. Hepatology. 2018 11; 68(5):1726-1740.
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TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway. Emerg Microbes Infect. 2018 Aug 08; 7(1):138.
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Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility. PLoS One. 2018; 13(7):e0197561.
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Biallelic inactivating variants in the GTPBP2 gene cause a neurodevelopmental disorder with severe intellectual disability. Eur J Hum Genet. 2018 04; 26(4):592-598.
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Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion. J Immunol. 2017 12 15; 199(12):4142-4154.
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Substrates and Inhibitors of SAMHD1. PLoS One. 2017; 12(1):e0169052.
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V-ATPase/mTOR signaling regulates megalin-mediated apical endocytosis. Cell Rep. 2014 Jul 10; 8(1):10-9.
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SAMHD1 has differential impact on the efficacies of HIV nucleoside reverse transcriptase inhibitors. Antimicrob Agents Chemother. 2014 Aug; 58(8):4915-9.
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Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response. Cell Rep. 2013 Aug 29; 4(4):689-96.